Reasons for the application of medical ozone in the treatment of chronic purulent mesotympanitis
AU - Shakov VIu
AU - Edeleva AN
AB - Ozone-oxygen mixture (ozone concentration 600 microg/l)
was used in irrigations of the tympanic cavity in 52 patients
with chronic purulent mesotympanitis (CPM). The course
of the treatment consisted of 5-7 procedures. 18 CPM controls
received standard treatment without the irrigations. The
course of the ozone-oxygen irrigations produced good results:
ear discharge and tympanic mucosa inflammation stopped
in 81% of the irrigated patients, levels of myeloperoxidase
which marks inflammation reduced significantly, bactericidal
effects of the mixture were observed for all the detected
pathogens, antibiotic sensitivity of the bacteria rose.
Fast antiinflammatory result of ozone therapy was due not
only to its bactericidal effect but also via its antihypoxic
and immunomodulating mechanisms.
SO - Vestn Otorinolaringol 1999; (2):48-9
DP - 1999
TA - Vestn Otorinolaringol
PG - 48-9
UI - 99243081