Evaluation of Therapeutic Properties of OLEOZON® in the Treatment of Women
with Human Papilloma Virus (HPV) Uteri Cervix Infection
Ríos M.A., Aguilar O., Torres A., Hernández M., Menéndez S. and Amigó M.
(Cuba)
HPV is associated with cervical cancer and preceding lesions. Cervical
cancer is the second most common malignant tumor in the world, although its
tendency is to occupy a first place in some geographic zones, such as
Central and South America and the Caribbean region. In spite of several
studies made worldwide to establish effective therapeutics against HPV
infection, there isn't consensus about this. Now there are two different
treatments for HPV infections. The first is based in lesion destruction by
mean of chemicals or surgical methods, but they can't eliminate viral
infection. The second one is based in viral elimination with antiviral
agents. The ozonized sunflower oil (OLEOZON®) has shown antiviral activity
in the treatment of viral infections such as Herpes virus. Our main aim in
this study was to evaluate the therapeutic efficacy of this product in HPV
infected women. To develop this study we selected 12 women with NIC I,
associated with HPV and condiloma acuminate lesions. OLEOZONŽ was applied
daily, in the uteri cervix of each patient, during 20 days. Cytological,
histological (in some cases) and colposcopic examination were made to each
patient before and after the treatment. Two of the twelve left the
treatment. From the rest, eight (80 %) women showed total clinical and
cytological regression of lesions. Viral persistence was observed in two (20
%) patients. In some cases, total elimination of vaginal secretion, was
observed after the treatment. Side effects due to the OLEOZON® were not
observed in any case.