Intravenous Ozone-Therapy Applications for the Treatment of Sensorineural Deafness with Various Genesis
25-8-06
Barkhotkina T. (Russia)
The purpose of the present work is to study the influence of parenteral applications of ozonized
physiological solution to the auditory function status of patients with sensorineural deafness.
This includes its postinfectious, vascular, toxic and posttraumatic genesis. The criteria, of the
treatment clinical efficiency, are the threshold pure tone audiometry and a number of other standard
audiological tests, such as the subjective noise presence (SN), the dynamics of whispered (WS) and
conversational speech (CS) appreciation and the change of mean hearing loss (MHL) during the inpatient
treatment. The positive results of therapy are evidence of the appreciable amelioration of an auditory
analyzer function, resulting from the intravenous ozonized physiological solution introductions. The WS
increment averaged is 2.26 m, CS - 2.1 m, MHL reduction - up to 19 dB . The clinical efficiency is
confirmed with the optimization of lipid peroxidation-antioxidant system (LP-AOS) state, energy
metabolism and immune status with this category of patients. The state of peripheral blood erythrocytes
has also been researched by a method of holographic interference microscopy. Today, the live fringes
holographic interferometry is only one method of determining the phase microobjects, in particular
erythrocytes in their native forms at real time. It is recognized, that all the sensorineural hard
of hearing patients, regardless of etiology and prescription of disease, have erythrocytes as flat
disks. There are slugged erythrocytes and blood microclots. As a result of parenteral ozone therapy
the one-type qualitative changes of the erythrocytes forms are to be observed. They acquire the
biconcave disocyte form corresponding to physiological pattern and have a wholesome influence on
the state of the organism. Analyzing the data, it is possible to establish the high efficiency of
ozone therapy in the treatment of acoustic analyzer pathology based on correcting the main parts
of the disease pathogenesis.