Is There a Role for Medical Ozone in the Treatment of HIV
and Associated Infections?
DT: Sept. 1993
AU: Michael T. Carpendale and John Griffiss
SO: Rehabilitation Medicine and Research Services, Veterans
Administration Medical Center, San Francisco, CA.
AB: Medical Ozone inactivates many pathogenic viruses including
HIV in vitro. Pilot studies in man suggest positive
benefits in the early stages of HIV infection (T-4 cells
greater than 400). These include increased T4 and T8 cells,
normalizing of T4:T8 ratio, and a general feeling of well-
being and minimal evidence of infection. Improvement also
occurs in AIDS patients (T4 cells less than 200) but less
evidence of T4 cell resurgence. These studies indicate that
at least in vitro there is a good safety margin between the
ozone dose required to inactivate HIV and the earliest
suggestion of suppression of lymphocytes. In fact, the
lymphocytes are being stimulated at doses that completely
inactivates HIV. More work needs to be done to clarify the
most effective dosage and means of treating HIV infections
with medical ozone.