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Lipid Peroxidation In Oncologic Patients Treated With Ozone Therapy

T.Scherbatyuk, M.Goryachev; Yu.Samochvalova and E.Polinkina.

Medical Academy, Nizhni Novgorod, Russia.

In recent years, radiation therapy of malignant tumours has undergone large changes due to the search for methods of selective radiosensitiveness, in order to increase the therapeutic interval between tumoral and normal tissues. With the purpose of intensifying the action of ionizing radiations, intravenous ozonized saline solution, before radiation, were applied in patients suffering from malignant diseases. 26 female patients with the diagnosis of malignant tumours, stage III and IV (uterus and ovary cancer and hysterocarcinoma) were studied. The treatment for the patients of the first group included the use of a fractionated gamma therapy (radiation dose for operated patients - 40 gp and for not operated - 70 gp). To the second group, 3 sessions of ozone therapy, before the gamma therapy was applied. A greater increase in the peroxidation processes and a greater decrease of the antioxidant defense system was found, after the sessions of radiation therapy, in the first group, in comparison with the second group, using ozonized saline solution.

Source: 3rd International Symposia on Ozone Applications, June 2000.



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