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Local Ozone Therapy For Delayed Scarring In Cancer Patients

G. Rovira (a), L. López (a), G. Suárez (b), M. Santana (b), B. Clavo (b), J.L. Pérez (b), M. Lloret (b), V. Rodríguez (c), D. Macías (b), M.A. Hernández (b), R. Martín (b) and F. Robaina (b)

(a) Quiron Clinic: Ozonetherapy Unit, Barcelona
(b) Dr. Negrin Hospital: Radiation Oncology-ResearchUnit, Medical Physics Unit, Chronic Pain Unit, Las Palmas
(c) La Paterna Medical Center, Las Palmas, Spain.

Hyperbaric chambers and local ozonetherapy are procedures to treat ischemic wounds and delayed scarring in cancer patients. Wounds in irradiated areas heal slowly and, sometimes, surgical wounds can delay the beginning of the chemotherapy and/or radiotherapy. We show our experience treating these wounds with ozone therapy. From 1990 to 1999 our hospitals have treated 28 patients with delayed scarring, 12 in previously irradiated areas. Surgery has been carried out without success in 7 occasions. Male: Female 10 : 18. Age: 55 ± 14 (21 - 94). Scars were 56 ± 48 (12 - 182) days old. Areas were 43 ± 79 (0.6 - 293) cm2. Fourteen scars were in breast cancer patients. The O3/O2 gas mixture was generated from medical oxygen at concentration of 20 - 70 ug/mL.. ozone therapy was carried out by local techniques (bags, catheters), 23 - 30 minutes 1 - 3 times/week. During ozone therapy, two wounds received radiotherapy and 7 chemotherapy. Data are showed as: Mean ± standard deviation (minimum-maximum). Scars were healed in 27 ± 11 (4 - 150) days, with 7 ± 3 (2 - 22) ozone therapy sessions. In eleven patients programmed surgery was avoided. Local ozone therapy is an useful treatment: to: A) accelerate healing wounds in previously irradiated areas B) avoid delays to start chemotherapy and/or radiotherapy in patients with delayed scarring after oncologic surgery.

Source: 3rd International Symposia on Ozone Applications, June 2000.



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