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Medical Ozone in the Treatment of lower Extremities Peripheral Circulation Disorders

S.N. Gorbunov, N.A. Mironov, S.P. Alyokhina, G.M. Pikalova

Nizhegorodski Reginal Hospital of War Veterans
Ozon Therapy Center
N. Novgorod
Russia

Atherosclerotic vessels disorders of the lower extremities are the most common pathology in advanced age groups of patients. It is considered to be one of the "civiliration discase" manifestations that lead to non-healing trophic ulcers and even to gangrene of extremities, that might cause invalidism and in some cases results in fatal outcomes. The common treatment to prevent atherosclerotic disorders and the use of vasodilators do not prove to be effective. Surgical interventions into vegetative nervous system provide a rare steady clinical effect either.

We have observed 132 patients in the age group of 62-84, all of them being war invalids with III-IV grade peripheral circulation disorder in lower extremities. All the patients had intermittent clandication, shorting of walking distance down to 150-200 m, cooling in the extremities and pains in calf muscles (musculus gastrocnemius), 31 patients had circulation disorders complicated by trophic ulcers the size of which being in the range of 5-32 sg. cm and duration in the range of 2-18 years.

11 patients had crus and femur wounds of 47-50 years standing. Anamnesis of 8 patients indicated frostbite episodes during the war. All the patients had repeatedly received traditional medical treatment before ozone therapy was administered, 3 patients having had unilateral and bilateral sympathectomy. It should be noted that while ozonetherapy was administered to all the patients, its methods were different.

The first group of patients received 8-10 intravenous injections of ozonesaturated rheopolyglucin solutions (rheamacrodex) in the dosage of 400,0 ml.

In the second group of patients intravenous ozone administration was combined with subcutaneous injections of gaseous ozone.

The third group of patients in addition to the first tow methods of ozone introduction received 3-4 seance of major ozone autohematherapy (AHT).

Patients with trophical ulcers were administered external ozonization in plastic bags. By the end of the treatment course all the patients noted significant improvement of their well-being with clinical evidence of the lack of pains or cramps in calf muscles and warming of the extremities. There was also noted a 10-15 fold increase in the walking distance. The combined ozonetherapy provided the most rapid clinical improvement. There increased blood saturation with oxygen and its voltage in vascular bed (channel) and tissues. In all the cases the ulcerous surface epitalization rate was up to 2-4 sq. cm a day. In two patients ozonated vulvosorbtion was done to stimulate the epitalization process. Surgical intervention was not needed for the heavy of trophic ulcers. The received data prove complex ozonetherapy to be highly effective in the treatment of lower extremities peripheral circulation disorders in the patients of the advanced age group.

Date: 1995



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